Development of One-Shot/One-Pot Borylation Reactions toward Organoboron-Based Materials

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One-pot borylation/amination reactions: syntheses of arylamine boronate esters from halogenated arenes.

[reaction: see text] A one-pot protocol for converting 1,3- and 1,4-substituted aryl halides to arylamine boronate esters is described. This is achieved by sequential Ir-catalyzed aromatic borylation at the least hindered C-H bond of the aryl halide and subsequent Pd-catalyzed C-N coupling at the halide position of the crude arylboronic ester.

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ژورنال

عنوان ژورنال: Bulletin of the Chemical Society of Japan

سال: 2021

ISSN: 0009-2673,1348-0634

DOI: 10.1246/bcsj.20200372